Kristian Alfsnes
forsker, Ph.D
Kontakt
Avdeling
Prosjekter og publikasjoner
- Building Stronger Public Health Institutions and Systems (BIS)
- Consolidation of the HERA-WGS-infrastructure and capacity building at NIPH to enhance microbial surveillance and preparedness
- Genom-epidemiologi og modellering av gonoré i Noreg
- TBFVNET: SURVEILLANCE AND RESEARCH ON TICK-BORNE FLAVIVIRUSES (TBFV)
- Magnus Nygård Osnes, Ola Brønstad Brynildsrud, Kristian Alfsnes, Lucy van Dorp, Samantha A McKeand, Jonathan Ross, Francois Balloux, Dominique Andree Yette Caugant, Yonathan H. Grad, Deborah A. Williamson, Katy Town, Jolinda de Korne-Elenbaas, Alje P. Van Dam, Sylvia Bruisten, Birgitte Freiesleben de Blasio, Xavier Didelot, Vegard Eldholm, (2023). The inter-continental population dynamics of Neisseria gonorrhoeae. eLIFE doi: 10.7554/eLife.90062.1
- Alaka Lamsal, Kristin Skarsfjord Edgar, Andrew Jenkins, Hans Renssen, Lene Jung Kjær, Kristian Alfsnes, Srijana Bastakoti, Malene Strøm Dieseth, Kirstine Klitgaard, Heidi Elisabeth Heggen Lindstedt, Katrine Mørk Paulsen, Rose Vikse, Lars Korslund, Vivian Kjelland, Snorre Stuen, Petter Kjellander, Madeleine Christensson, Malin Teräväinen, Laura Mark Jensen, Manoj Regmi, Dhiraj Giri, Leif Marsteen, René Bødker, Arnulf Soleng, Åshild Kristine Andreassen, (2023). Prevalence of tick-borne encephalitis virus in questing Ixodes ricinus nymphs in southern Scandinavia and the possible influence of meteorological factors. Zoonoses and Public Health s. 473-484. doi: 10.1111/zph.13049
- Ola Brønstad Brynildsrud, Sara Sofie Viksmoen Watle, Kristian Alfsnes, Dominique A. Caugant, (2023). Invasive meningococcal disease in Norway in the two decades before the COVID-19 pandemic. International Journal of Infectious Diseases s. 130-139. doi: 10.1016/j.ijid.2023.04.005
- Linn Merete B. Corwin, André Ingebretsen, Patricia Campbell, Kristian Alfsnes, Fredrik Müller, Norman Mauder, Michael Koomey, Jørgen Bjørnholt, (2023). Fourier transform infrared spectroscopy; can it be used as a rapid typing method of Neisseria gonorrhoeae?. Journal of Microbiological Methods s. 1-9. doi: 10.1016/j.mimet.2023.106675
- Hilde Synnøve Vollan, Dominique Andree Yvette Caugant, Vegard Eldholm, Kristian Alfsnes, Nadia Debech, Ola Brønstad Brynildsrud, (2022). Naturally occurring Neisseria gonorrhoeae can have large deletions in housekeeping gene abcZ, making them untypable with multilocus sequence typing. Microbial Genomics doi: 10.1099/mgen.0.000889
- Kristian Alfsnes, Nina Lagerqvist, Sirkka Vene, Jon Bohlin, Jenny Verner-Carlsson, David Ekqvist, Andreas Bråve, Edward C. Holmes, Weifeng Shi, John H.-O. Pettersson, (2021). Retrospective meta-transcriptomic identification of severe dengue in a traveller returning from Africa to Sweden, 1990. One Health doi: 10.1016/j.onehlt.2021.100217
- Kristian Alfsnes, Vegard Eldholm, Michael W. Gaunt, Xavier de Lamballerie, Ernest A. Gould, John H.-O. Pettersson, (2021). Tracing and tracking the emergence, epidemiology and dispersal of dengue virus to Africa during the 20th century. One Health doi: 10.1016/j.onehlt.2021.100337
- Magnus Nygård Osnes, Kristian Alfsnes, Jon Bråte, Ignacio Garcia Llorente, Rasmus Kopperud Riis, Kamilla Heddeland Instefjord, Hilde Elshaug, Hilde Synnøve Vollan, Line Victoria Moen, Benedikte Nevjen Pedersen, Dominique Andree Yvette Caugant, Kathrine Stene-Johansen, Olav Hungnes, Karoline Bragstad, Ola Brønstad Brynildsrud, Vegard Eldholm, (2021). The impact of global lineage dynamics, border restrictions, and emergence of the B.1.1.7 lineage on the SARS-CoV-2 epidemic in Norway. Virus Evolution s. 1-7. doi: 10.1093/ve/veab086
- Daniel Abiriga, Andrew Jenkins, Kristian Alfsnes, Live Semb Vestgarden, Harald Klempe, (2021). Characterisation of the bacterial microbiota of a landfill-contaminated confined aquifer undergoing intrinsic remediation. Science of the Total Environment doi: 10.1016/j.scitotenv.2021.147349
- Daniel Abiriga, Andrew Jenkins, Kristian Alfsnes, Live Semb Vestgarden, Harald Klempe, (2021). Spatiotemporal and seasonal dynamics in the microbial communities of a landfill-leachate contaminated aquifer. FEMS Microbiology Ecology s. 1-11. doi: 10.1093/femsec/fiab086
- Magnus Nygård Osnes, Lucy van Dorp, Ola Brønstad Brynildsrud, Kristian Alfsnes, Thamarai Schneiders, Kate E. Templeton, Koji Yahara, Francois Balloux, Dominique Andree Yvette Caugant, Vegard Eldholm, (2020). Antibiotic treatment regimes as a driver of the global population dynamics of a major gonorrhea lineage. Molecular Biology and Evolution (MBE) s. 1-13. doi: 10.1093/molbev/msaa282
- Katrine Mørk Paulsen, Alaka Lamsal, Srijana Bastakoti, John Pettersson, Benedikte Pedersen, Karin Stiasny, Mats Haglund, Teemu Smura, Olli Vapalahti, Rose Vikse, Kristian Alfsnes, Åshild Kristine Andreassen, (2020). High-throughput sequencing of two European strains of tick-borne encephalitis virus (TBEV), Hochosterwitz and 1993/783. Ticks and Tick-borne Diseases doi: 10.1016/j.ttbdis.2020.101557
- Magnus Nygård Osnes, Xavier Didelot, Jolinda de Korne-Elenbaas, Kristian Alfsnes, Ola Brønstad Brynildsrud, Gaute Syversen, Øivind Jul Nilsen, Birgitte Freiesleben de Blasio, Dominique A Caugant, Vegard Eldholm, (2020). Sudden emergence of a Neisseria gonorrhoeae clade with reduced susceptibility to extended-spectrum cephalosporins, Norway. Microbial Genomics doi: 10.1099/mgen.0.000480
- Kristian Alfsnes, Vegard Eldholm, Anne Olaug Olsen, Ola Brønstad Brynildsrud, Jon Bohlin, Martin Steinbakk, Dominique A Caugant, (2020). Genomic epidemiology and population structure of Neisseria gonorrhoeae in Norway, 2016–2017. Microbial Genomics doi: 10.1099/mgen.0.000359
- John Pettersson, Geraldine Piorkowski, Mayfong Mayxay, Sayaphet Rattanavong, Manivanh Vongsouvath, Viengmon Davong, Kristian Alfsnes, Vegard Eldholm, Xavier de Lamballerie, Edward C. Holmes, Paul N. Newton, Audrey Dubot-Pérès, (2019). Meta-transcriptomic identification of hepatitis B virus in cerebrospinal fluid in patients with central nervous system disease. Diagnostic microbiology and infectious disease s. 1-4. doi: 10.1016/j.diagmicrobio.2019.114878
- Lotta Linnea Siira, Mohammed Umaer Naseer, Kristian Alfsnes, Nils Olav Hermansen, Heidi Lange, Lin Cathrine T. Brandal, (2019). Whole genome sequencing of Salmonella Chester reveals geographically distinct clusters, Norway, 2000 to 2016. Eurosurveillance doi: 10.2807/1560-7917.ES.2019.24.4.1800186
- Diepreye Ayabina, Janne Oseberg Rønning, Kristian Alfsnes, Nadia Debech, Ola Brønstad Brynildsrud, Trude Margrete Arnesen, Gunnstein Norheim, Anne Torunn Mengshoel, Rikard Rykkvin, Ulf R Dahle, Caroline Colijn, Vegard Eldholm, (2018). Genome-based transmission modelling separates imported tuberculosis from recent transmission within an immigrant population. Microbial Genomics doi: 10.1099/mgen.0.000219
- Ola Brønstad Brynildsrud, Caitlin S. Pepperell, Philip Suffys, Louis Grandjean, Johana Monteserin, Nadia Debech, Jon Bohlin, Kristian Alfsnes, John Pettersson, Ingerid Ørjansen Kirkeleite, Fatima Fandinho, Marcia Aparecida da Silva, Joao Perdigao, Isabel Portugal, Miguel Viveiros, Taane Clark, Maxine Caws, Sarah Dunstan, Phan Vuong Khac Thai, Beatriz López, Viviana Ritacco, Andrew Kitchen, Tyler S. Brown, Dick van Soolingen, Mary B. O'Neill, Kathryn E. Holt, Edward J. Feil, Barun Mathema, Francois Balloux, Vegard Eldholm, (2018). Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation. Science Advances doi: 10.1126/sciadv.aat5869
- Kristian Alfsnes, Stephan Alfons Frye, Jens Eriksson, Vegard Eldholm, Ola Brønstad Brynildsrud, Jon Bohlin, Odile B Harrison, D Hood, Martin C.J. Maiden, Tone Tonjum, Ole Herman Ambur, (2018). A genomic view of experimental intraspecies and interspecies transformation of a rifampicin-resistance allele into Neisseria meningitidis. Microbial Genomics s. 1-14. doi: 10.1099/mgen.0.000222
- Jon Bohlin, Vegard Eldholm, Ola Brønstad Brynildsrud, John Pettersson, Kristian Alfsnes, (2018). Modeling of the GC content of the substituted bases in bacterial core genomes. BMC Genomics doi: 10.1186/s12864-018-4984-3
- John Pettersson, Jon Bohlin, Myrielle Dupont-Rouzeyrol, Ola Brønstad Brynildsrud, Kristian Alfsnes, Van-Mai Cao-Lormeau, Michael W Gaunt, Andrew K Falconar, Xavier de Lamballerie, Vegard Eldholm, Didier Musso, Ernest A Gould, (2018). Re-visiting the evolution, dispersal and epidemiology of Zika virus in Asia. Emerging microbes & infections doi: 10.1038/s41426-018-0082-5
- Per Kristian Knudsen, Karianne Wiger Gammelsrud, Kristian Alfsnes, Martin Steinbakk, Tore G Abrahamsen, Fredrik Müller, Jon Bohlin, (2018). Transfer of a bla CTX-M-1-carrying plasmid between different Escherichia coli strains within the human gut explored by whole genome sequencing analyses. Scientific Reports doi: 10.1038/s41598-017-18659-2
- Kristian Alfsnes, Hans Petter Leinaas, Dag Olav Hessen, (2017). Genome size in arthropods; different roles of phylogeny, habitat and life history in insects and crustaceans. Ecology and Evolution s. 5939-5947. doi: 10.1002/ece3.3163
- Dag Olav Hessen, Ingunn Tombre, Gerben van Geest, Kristian Alfsnes, (2017). Global change and ecosystem connectivity: how geese link fields of central Europe to eutrophication of Arctic freshwaters. Ambio s. 40-47. doi: 10.1007/s13280-016-0802-9
- Vegard Eldholm, John Pettersson, Ola Brønstad Brynildsrud, Andrew Kitchen, Erik Michael Rasmussen, Troels Lillebæk, Janne Oseberg Rønning, Valeriu Crudu, ANNE TORUNN MENGSHOEL, Nadia Debech, Kristian Alfsnes, Jon Bohlin, Caitlin S. Pepperell, Francois Balloux, (2016). Armed conflict and population displacement as drivers of the evolution and dispersal of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America (PNAS) s. 13881-13886. doi: 10.1073/pnas.1611283113
- Kristian Alfsnes, Anders Hobæk, Lawrence J. Weider, Dag O. Hessen, (2016). Birds, nutrients, and climate change: mtDNA haplotype diversity of Arctic Daphnia on Svalbard revisited. Polar Biology s. 1425-1437. doi: 10.1007/s00300-015-1868-8
- Elisabeth Schrumpf, Corey Tan, Tom Hemming Karlsen, Jon Sponheim, Niklas K. Björkström, Olav Sundnes, Kristian Alfsnes, Arthur Kaser, Douglas M. Jefferson, Yoshiyuki Ueno, Tor Jacob Eide, Guttorm Haraldsen, Sebastian Zeissig, Mark A. Exley, Richard S. Blumberg, Espen Melum, (2015). The biliary epithelium presents antigens to and activates natural killer T cells. Hepatology s. 1249-1259. doi: 10.1002/hep.27840
- Kristian Alfsnes, Xavier Raynaud, Tone Tonjum, Ole Herman Ambur, (2014). Mathematical and live meningococcal models for simple sequence repeat dynamics - Coherent predictions and observations. PLOS ONE doi: 10.1371/journal.pone.0101637
- Afsaneh Vahdani-Benam, Emma Helena Lång, Kristian Alfsnes, Burkhard Fleckenstein, Alexander D. Rowe, Eirik Hovland, Ole Herman Ambur, Stephan Alfons Frye, Tone Tønjum, (2011). Structure-function relationships of the competence lipoprotein ComL and SSB in meningococcal transformation. Microbiology (Reading) s. 1329-1342. doi: 10.1099/mic.0.046896-0
- Katrina Louise Bø Tibballs, Ole Herman Ambur, Kristian Alfsnes, Håvard Homberset, Stephan Alfons Frye, Tonje Davidsen, Tone Tønjum, (2009). Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair. BMC Microbiology doi: 10.1186/1471-2180-9-7
- Kristian Alfsnes, OB Harrison, P Power, S Bentley, Stephan Alfons Frye, Martin CJ Maiden, D Hood, Tone Tønjum, Ole Herman Ambur, (2012). Intergenic crossover hotspots in meningococcal transformation.
- Kristian Alfsnes, P Power, S Bentley, K. Makepeace, Ole Herman Ambur, Tone Tønjum, D Hood, (2010). Genome-wide effects of transformation, mutation and phase variation in Neisseria meningitidis.
- Ole Herman Ambur, Kristian Alfsnes, Eirik Hovland, Håvard Homberset, Jon Kristen Lærdahl, Stephan Alfons Frye, Torbjørn Rognes, Mari Støen, Tone Tønjum, (2010). Mechanisms of neisserial transformation and the evolution of sexual reproduction.
- Kristian Alfsnes, Marie Bergem-Ohr, Ole Herman Ambur, Tone Tønjum, (2008). Impact of defects in DNA repair genes on genome instability and phase variation in Neisseria meningitidis.
- Stephan Alfons Frye, Ole Herman Ambur, Tone Tønjum, Seetha Balasingham, Emma Lång, Kristian Alfsnes, Håvard Homberset, Tonje Davidsen, Afsaneh Vahdani-Benam, (2007). News on DUS.