Gro Tunheim
forsker, PhD i immunologi
Kontakt
Mob: 415 25 656
Avdeling
Fagområder
cand.pharm, PhD i immunologi
Prosjekter og publikasjoner
- Den norske influensastudien (NorFlu)
- Husholdsmitte og immunrespons etter koronavirus infeksjon
- Immunitet i befolkningen i Norge
- NON-PROTECTED. The impact of perfluorinated toxicants and the gut microbiome on vaccine responses in children (Forskerprosjekt - FRIMEDBIO).
- Seroprevalens mot SARS-CoV-2 i befolkningen i Norge målt i restsera
- Seroprevalensstudie for kikhoste og andre vaksineforebyggbare sykdommer i Norge
- Gro Tunheim, Even Fossum, Anna Hayman Robertson, Gunnar Øyvind Isaksson Rø, Adity Chopra, John T. Vaage, Elisabeth Lea Vikse, Anne-Marte Bakken Kran, Per Minor Magnus, Lill Trogstad, Siri Mjaaland, Olav Hungnes, Fridtjof Lund-Johansen, (2024). Characterization of the SARS-CoV-2 antibody landscape in Norway in the late summer of 2022: high seroprevalence in all age groups with patterns of primary Omicron infection in children and hybrid immunity in adults. BMC Infectious Diseases s. 1-20. doi: 10.1186/s12879-024-09670-w
- Sara Viksmoen Watle, Bente Børud, Ida Laake, Marta Natalia Baranowska-Hustad, Diane Lynn Bryant-Bratlie, Terese Bekkevold, Dominique A. Caugant, Gro Tunheim, Lisbeth Meyer Næss, (2023). Antibodies against Neisseria meningitidis serogroups A, C, W and Y in serum and saliva of Norwegian adolescents. Vaccine s. 6529-6537. doi: 10.1016/j.vaccine.2023.08.052
- Gro Tunheim, Gunnar Øyvind Isaksson Rø, Adity Chopra, Audun Aase, Anne-Marte Bakken Kran, John T. Vaage, Fridtjof Lund-Johansen, Olav Hungnes, (2022). Prevalence of antibodies against SARS-CoV-2 in the Norwegian population, August 2021. Influenza and Other Respiratory Viruses s. 1004-1013. doi: 10.1111/irv.13024
- Torgun Wæhre, Gro Tunheim, Johanna Eva Bodin, Ida Laake, Dag Kvale, Anne-Marte Bakken Kran, Hanne Brekke, Ragnhild Øye Løken, Fredrik Oftung, Siri Mjaaland, Anne Margarita Dyrhol Riise, (2022). Clinical characteristics and outcomes in hospitalized adult influenza patients: an observational study from Norway 2014-2018. Infectious Diseases s. 367-377. doi: 10.1080/23744235.2021.2022196
- Cathinka Halle Julin, Anna Hayman Robertson, Olav Hungnes, Gro Tunheim, Terese Bekkevold, Ida Laake, Idunn Forland Aune, Marit Fodnes Killengreen, Torunn Ramsem Strand, Rikard Rykkvin, DAGNY HAUG DORENBERG, Kathrine Stene-Johansen, Einar Sverre Berg, Johanna Eva Bodin, Fredrik Oftung, Anneke Steens, Lisbeth Meyer Næss, (2021). Household transmission of sars-cov-2: A prospective longitudinal study showing higher viral load and increased transmissibility of the alpha variant compared to previous strains. Microorganisms s. 1-19. doi: 10.3390/microorganisms9112371
- Gro Tunheim, Gunnar Øyvind Isaksson Rø, Trung Tran, Anne-Marte Bakken Kran, Jan Terje Andersen, Eline Benno Vaage, Anette Kolderup, John T. Vaage, Fridtjof Lund-Johansen, Olav Hungnes, (2021). Trends in seroprevalence of SARS-CoV-2 and infection fatality rate in the Norwegian population through the first year of the COVID-19 pandemic. Influenza and Other Respiratory Viruses s. 204-212. doi: 10.1111/irv.12932
- Sara Sofie Viksmoen Watle, Lisbeth Meyer Næss, Gro Tunheim, Dominique A Caugant, Torbjørn Wisløff, (2021). Cost-effectiveness of meningococcal vaccination of Norwegian teenagers with a quadrivalent ACWY conjugate vaccine. Human Vaccines & Immunotherapeutics s. 2777-2787. doi: 10.1080/21645515.2021.1880209
- Sara Sofie Viksmoen Watle, Dominique A Caugant, Gro Tunheim, Terese Bekkevold, Ida Laake, Ola Brønstad Brynildsrud, Lisbeth Meyer Næss, (2020). Meningococcal carriage in Norwegian teenagers: strain characterisation and assessment of risk factors. Epidemiology and Infection s. 1-12. doi: 10.1017/S0950268820000734
- Anna Hayman Robertson, Milada Mahic, Miloje Savic, Gro Tunheim, Olav Hungnes, Lill Trogstad, Walter Ian Lipkin, Siri Mjaaland, (2020). Detection of anti‐NS1 antibodies after pandemic influenza exposure: Evaluation of a serological method for distinguishing H1N1pdm09 infected from vaccinated cases. Influenza and Other Respiratory Viruses s. 294-301. doi: 10.1111/irv.12712
- Gro Tunheim, Ida Laake, Anna Hayman Robertson, Kristian Waalen, Olav Hungnes, Lisbeth Meyer Næss, Rebecca Jane Cox, Siri Mjaaland, Lill Trogstad, (2018). Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self-reported severity and duration of illness. Influenza and Other Respiratory Viruses s. 191-200. doi: 10.1111/irv.12623
- Ida Laake, Gro Tunheim, Anna Hayman Robertson, Olav Hungnes, Kristian Waalen, Siri Eldevik Håberg, Siri Mjaaland, Lill Trogstad, (2018). Risk of pregnancy complications and adverse birth outcomes after maternal A(H1N1)pdm09 influenza: a Norwegian population-based cohort study. BMC Infectious Diseases doi: 10.1186/s12879-018-3435-8
- Reinaldo Acevedo, Caridad Zayas, Gunnstein Norheim, Sonsire Fernández, Barbara Cedré, Yisabel Aranguren, Maribel Cuello, Yaimara Rodriguez, Fernando Gonzalez, Aleida Mandiarote, Marylin Perez, Maritza Hernández, Mabel Hernández-Cedeno, Domingo Gonzalez, Sverre Henning Brorson, Einar Rosenqvist, Lisbeth Meyer Næss, Gro Tunheim, Daniel Cardoso, Luis Garcia, (2017). Outer membrane vesicles extracted from Neisseria meningitidis serogroup X for prevention of meningococcal disease in Africa. Pharmacological Research s. 194-201. doi: 10.1016/j.phrs.2017.04.030
- Gro Tunheim, Marianne Arnemo, Lisbeth Meyer Næss, Gunnstein Norheim, Luis Garcia, Daniel Cardoso, Aleida Mandiarote, Domingo Gonzalez, Kalpana Sinnadurai, Åse-Karine Fjeldheim, Karin Bolstad, Einar Rosenqvist, (2016). Immune responses of a meningococcal A + W outer membrane vesicle (OMV) vaccine with and without aluminium hydroxide adjuvant in two different mouse strains. APMIS - Journal of Pathologiy, Microbiology and Immunology s. 996-1003. doi: 10.1111/apm.12589
- Maria Christine Magnus, Øystein Karlstad, Øivind Midttun, Siri Eldevik Håberg, Gro Tunheim, Christine Louise Parr, Per Nafstad, Stephanie J London, Roy Miodini Nilsen, Per Magne Ueland, Wenche Nystad, (2016). Maternal plasma total neopterin and kynurenine/tryptophan levels during pregnancy in relation to asthma development in the offspring. Journal of Allergy and Clinical Immunology s. 1319-1325.e4. doi: 10.1016/j.jaci.2016.02.032
- Jennifer Lynn Dembinski, Miloje Savic, Yohan Kim, Gro Tunheim, Rebecca Jane Cox, Fredrik Oftung, Bjørn Peters, Siri Mjaaland, (2016). Epitope specific T-cell responses against influenza A in a healthy population. Immunology s. 165-177. doi: 10.1111/imm.12548
- Kristin Greve Isdahl Mohn, Rebecca Jane Cox, Gro Tunheim, Jan Erik Berdal, Anna G Hauge, Åsne Jul-Larsen, Bjørn Peters, Fredrik Oftung, Christine M Jonassen, Siri Mjaaland, (2015). Immune responses in acute and convalescent patients with mild, moderate and severe disease during the 2009 influenza pandemic in Norway. PLOS ONE doi: 10.1371/journal.pone.0143281
- Gro Tunheim, Lisbeth Meyer Næss, R Acevedo, Åse-Karine Fjeldheim, Karin Bolstad, L Garcia, D Cardoso, Audun Aase, C Zayas, H Gonzalez, Einar Rosenqvist, Gunnstein Norheim, (2014). Preclinical immunogenicity study of trivalent meningococcal AWX-OMV vaccines for the African meningitis belt. Vaccine s. 6631-6638. doi: 10.1016/j.vaccine.2014.09.063
- M Medhane, Gro Tunheim, Lisbeth Meyer Næss, W Mihret, A Bedru, Gunnstein Norheim, B Petros, A Aseffa, Einar Rosenqvist, (2014). Avidity of IgG antibodies against meningococcal serogroup a polysaccharide and correlations with bactericidal activity in sera from meningitis patients and controls from ethiopia. Scandinavian Journal of Immunology s. 267-275. doi: 10.1111/sji.12150
- Gunnveig Grødeland, Siri Mjaaland, Gro Tunheim, Agnete Fredriksen, Bjarne Bogen, (2013). The Specificity of Targeted Vaccines for APC Surface Molecules Influences the Immune Response Phenotype. PLOS ONE doi: 10.1371/journal.pone.0080008
- Gro Tunheim, Marianne Arnemo, Lisbeth Meyer Næss, Åse-Karine Fjeldheim, Lisa Nome, Karin Bolstad, Audun Aase, A Mandiarote, H Gonzalez, D Gonzalez, L Garcia, D Cardoso, Einar Rosenqvist, Gunnstein Norheim, (2013). Preclinical immunogenicity and functional activity studies of an A + W meningococcal outer membrane vesicle (OMV) vaccine and comparisons with existing meningococcal conjugate- and polysaccharide vaccines. Vaccine s. 6097-6106. doi: 10.1016/j.vaccine.2013.09.044
- Gunnstein Norheim, Gro Tunheim, Lisbeth Meyer Næss, Paul Arne Kristiansen, Dominique A Caugant, Einar Rosenqvist, (2012). An Outer Membrane Vesicle Vaccine for Prevention of Serogroup A and W-135 Meningococcal Disease in the African Meningitis Belt. Scandinavian Journal of Immunology s. 99-107. doi: 10.1111/j.1365-3083.2012.02709.x
- Gro Tunheim, Karoline W Schjetne, Ingunn B Rasmussen, Ludvig Magne Sollid, Inger Sandlie, Bjarne Bogen, (2008). Recombinant antibodies for delivery of antigen: a single loop between beta-strands in the constant region can accommodate long, complex and tandem T cell epitopes. International Immunology doi: 10.1093/intimm/dxm141
- G Tunheim, KM Thompson, AB Fredriksen, Terje Espevik, KW Schjetne, B Bogen, (2007). Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates. Vaccine s. 4723-4734. doi: 10.1016/j.vaccine.2007.04.004
- Harald Husebye, Øyvind Halaas, Harald Stenmark, G Tunheim, Øystein Sandanger, B Bogen, A Brech, Eicke Latz, Terje Espevik, (2006). Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO Journal s. 683-692.
- Gro Tunheim, Karoline W Schjetne, Agnete Brunsvik, Inger Sandlie, Bjarne Bogen, (2005). Human CD14 is an efficient target for recombinant immunoglobulin vaccine constructs that deliver T cell epitopes. Journal of Leukocyte Biology
- Gro Tunheim, Karoline W Schjetne, Inger Sandlie, Bjarne Bogen, (2004). Nye vaksiner basert på Troybodies. Norsk Farmaceutisk Tidsskrift (NFT)
- Gro Tunheim, Anne-Marte Bakken Kran, Gunnar Øyvind Isaksson Rø, Olav Hungnes, Fridtjof Lund-Johansen, Eline Benno Vaage, Trung Tran, Jan Andersen, John T. Vaage, (2021). Seroprevalence of SARS-CoV-2 in the Norwegian population measured in residual sera collected in January 2021 .
- Gro Tunheim, Anne-Marte Bakken Kran, Gunnar Øyvind Isaksson Rø, Olav Hungnes, Fridtjof Lund-Johansen, Trung Tran, Jan Terje Andersen, John T. Vaage, (2020). Seroprevalence of SARS-CoV-2 in the Norwegian population measured in residual sera collected in late summer 2020.
- Gro Tunheim, Anne-Marte Bakken Kran, Gunnar Øyvind Isaksson Rø, Anneke Steens, Olav Hungnes, Fridtjof Lund-Johansen, Trung Tran, Jan Terje Andersen, John T. Vaage, (2020). Seroprevalence of SARS-CoV-2 in the Norwegian population measured in residual sera collected in April/May 2020 and August 2019.
- Are Stuwitz Berg, Ellen Furuseth, Margrethe Greve-Isdahl, Ivar Wilhelm Grosvold, Lisbeth Meyer Næss, Hanne Magdalene Nøkleby, Jeanette Stålkrantz, Gro Tunheim, Torbjørn Wisløff, Britt Wolden, Ingeborg Sundsvalen Aaberge, Audun Aase, (2019). Kikhostevaksine til gravide – aktuelt for Norge?.
- Gro Tunheim, (2006). Recombinant antibody-based vaccines.
- Gro Tunheim, Ida Laake, Anna Hayman Robertson, Kristian Waalen, Olav Hungnes, Siri Mjaaland, Lill Trogstad, (2016). Antibody levels in pregnant women after A(H1N1)pdm09 infection or vaccination: association with clinical disease, self-reported symptoms and time since exposure.
- Ida Laake, Gro Tunheim, Anna Hayman Robertson, Olav Hungnes, Kristian Waalen, Siri Eldevik Håberg, Siri Mjaaland, Lill Trogstad, (2016). Risk of adverse pregnancy outcomes after A(H1N1)pdm09 infection.
- Miloje Savic, Ida Laake, Jennifer Lynn Dembinski, Gro Tunheim, Fredrik Oftung, Kristian Waalen, Olav Hungnes, Lisbeth Meyer Næss, Lill Trogstad, Rebecca Jane Cox, Siri Mjaaland, (2014). The Norwegian Influenza cohort study (NorFlu): immune responses in H1N1 pdm exposed versus non-exposed pregnant women.
- Lill Trogstad, Siri Mjaaland, Tor Molden, Ida Laake, Miloje Savic, Jennifer Lynn Dembinski, Gro Tunheim, Ingrid Borren, Synnve Schjølberg, Kristian Tambs, Willy Bjarne Eriksen, Anne-Siri Øyen, Patrica Schreuder, Anna Hayman Robertson, Gro Ellen Korsvold, Ingvild Bokn, Stian Barbo Valand, Kristian Waalen, Olav Hungnes, Fredrik Oftung, Kari Kveim Lie, Lisbeth Meyer Næss, Rebecca Jane Cox, Camilla Stoltenberg, Per Magnus, Siri Eldevik Håberg, (2014). Perinatal outcomes and children’s health after prenatal exposure to influenza infection and vaccination.
- Miloje Savic, Ida Laake, Jennifer Lynn Dembinski, Gro Tunheim, Fredrik Oftung, Olav Hungnes, Lisbeth Meyer Næss, Lill Trogstad, Rebecca Jane Cox, Siri Mjaaland, Kristian Waalen, (2014). The Norwegian Influenza cohort (NorFlu): immune responses in pdmH1N1 exposed versus non-exposed pregnant women.
- Lill Trogstad, Siri Mjaaland, Tor Molden, Ida Laake, Miloje Savic, Jennifer Lynn Dembinski, Gro Tunheim, Ingrid Borren, Synnve Schjølberg, Kristian Tambs, Willy Bjarne Eriksen, Anne-Siri Øyen, Anna Hayman Robertson, Gro Ellen Korsvold, Ingvild Bokn, Stian Barbo Valand, Olav Hungnes, Fredrik Oftung, Kari Kveim Lie, Lisbeth Meyer Næss, Rebecca Jane Cox, Per Magnus, Siri Eldevik Håberg, (2014). Perinatal outcomes and children’s health after prenatal exposure to influenza infection and vaccination.
- Harald Husebye, Øyvind Halaas, Harald Stenmark, G Tunheim, Øystein Sandanger, A Brech, B Bogen, Eicke Latz, Terje Espevik, (2007). Functions associated with intracellular trafficking of Toll-like receptor 4. Poster award 3rd price.
- Harald Husebye, Øyvind Halaas, Harald Stenmark, G Tunheim, Øystein Sandanger, A Brech, B Bogen, Eicke Latz, Terje Espevik, (2006). Functions associated with intracellular traficking of Toll-like receptor 4.
- Harald Husebye, Øyvind Halaas, Harald Stenmark, G Tunheim, Øystein Sandanger, A Brech, B Bogen, Eicke Latz, Terje Espevik, (2006). Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.
- Harald Husebye, Øyvind Halaas, Harald Stenmark, G Tunheim, Øystein Sandanger, A Brech, B Bogen, Eicke Latz, Terje Espevik, (2006). Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.
- Gro Tunheim, Karoline Western Schjetne, Karoline Brunsvik, Gustav Gaudernack, (2002). New cancer vaccines based on Troybodies.
- Agnete Brunsvik, Karoline Western Schjetne, Gro Tunheim, Inger Sandlie, Bjarne Bogen, (2002). Construction of tetrabodies for cancer vaccines Construction of tetrabodies for cancer vaccines.