Carol Joanne Church Holm-Hansen
forsker, Dr. philos (PhD) 1995
Kontakt
Mob: 414 78 643
Avdeling
Fagområder
Tuberkulose, hiv/aids
Prosjekter og publikasjoner
- Solomon Abebe Yimer, Shewit Kalayou, Håvard Homberset, Alemayehu Godana Birhanu, Tahira Riaz, Ephrem Debebe Zegeye, Timo Lutter, Markos Abebe, Carol J.C. Holm-Hansen, Abraham Aseffa, Tone Tonjum, (2020). Lineage-specific proteomic signatures in the Mycobacterium tuberculosis complex reveal differential abundance of proteins involved in virulence, DNA repair, CRISPR-Cas, bioenergetics and lipid metabolism. Frontiers in Microbiology doi: 10.3389/fmicb.2020.550760
- Johanna Eva Bodin, Adane Mihret, Carol J C Holm-Hansen, Jennifer Lynn Dembinski, Mai Chi Trieu, Bamlak Tessema, Azeb Tarekegne, Abebe Yimer Solomon, Rebecca Jane Cox, Abraham Aseffa, Bjørn Haneberg, Siri Mjaaland, (2019). Vitamin D Deficiency is Associated with Increased Use of Antimicrobials among Preschool Girls in Ethiopia. Nutrients s. 1-14. doi: 10.3390/nu11030575
- Alemayehu Godana Birhanu, Abebe Yimer Solomon, Shewit Kalayou, Tahira Riaz, Ephrem Debebe Zegeye, Carol J C Holm-Hansen, Gunnstein Norheim, Abraham Aseffa, Markos Abebe, Tone Tonjum, (2019). Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex. Scientific Reports s. 1-15. doi: 10.1038/s41598-019-39654-9
- Alemayehu Godana Birhanu, Abebe Yimer Solomon, Carol J C Holm-Hansen, Gunnstein Norheim, Abraham Aseffa, Markose Abebe, Tone Tonjum, (2017). Nε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 strains: Proteins Involved in Bioenergetics, Virulence and Antimicrobial Resistance are Acetylated. Journal of Proteome Research s. 4045-4059. doi: 10.1021/acs.jproteome.7b00429
- Solomon Abebe Yimer, Alemayehu Godana Birhanu, Shewit Kalayou, Tahira Riaz, Ephrem Debebe Zegeye, Getachew Tesfaye Beyene, Carol J C Holm-Hansen, Gunnstein Norheim, Markose Abebe, Abraham Aseffa, Tone Tonjum, (2017). Comparative proteomic analysis of Mycobacterium tuberculosis lineage 7 and lineage 4 strains reveals differentially abundant proteins linked to slow growth and virulence. Frontiers in Microbiology s. 1-14. doi: 10.3389/fmicb.2017.00795
- Solomon Abebe Yimer, Amine Namouchi, Ephrem Debebe Zegeye, Carol J C Holm-Hansen, Gunnstein Norheim, Markos Abebe, Abraham Aseffa, Tone Tonjum, (2016). Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7. BMC Evolutionary Biology s. 1-10. doi: 10.1186/s12862-016-0715-z
- Hanna Nebenzahl-Guimaraes, Solomon Abebe Yimer, Carol J C Holm-Hansen, Jessica de Beer, Roland Brosch, Dick van Soolingen, (2016). Genomic characterization of Mycobacterium tuberculosis lineage 7 and a proposed name: ‘Aethiops vetus’. Microbial Genomics doi: 10.1099/mgen.0.000063
- Solomon Abebe Yimer, Gunnstein Norheim, Amine Namouchi, Ephrem Debebe Zegeye, Wibeke Kinander, Tone Tonjum, Shiferaw Bekele, Turid Mannsåker, Gunnar Aksel Bjune, Abraham Aseffa, Carol J C Holm-Hansen, (2015). Mycobacterium tuberculosis lineage 7 strains are associated with prolonged patient delay in seeking treatment for pulmonary tuberculosis in Amhara region, Ethiopia. Journal of Clinical Microbiology s. 1301-1309. doi: 10.1128/JCM.03566-14
- Kristin Brekke, Andreas Lind, Carol J C Holm-Hansen, Inger Lise Haugen, Birger Sørensen, Maja Sommerfelt, Dag Kvale, (2014). Intranasal administration of a therapeutic HIV vaccine (Vacc-4x) induces dose-dependent systemic and mucosal immune responses in a randomized controlled trial. PLOS ONE doi: 10.1371/journal.pone.0112556
- Solomon Abebe Yimer, Carol J C Holm-Hansen, Dag Gustav Gundersen Storla, Gunnar Aksel Bjune, (2014). Tuberculosis management time: an alternative parameter for measuring the tuberculosis infectious pool. Tropical medicine & international health s. 313-320. doi: 10.1111/tmi.12246
- Solomon Abebe Yimer, Gunnar Aksel Bjune, Carol J. C. Holm-Hansen, (2014). Time to first consultation, diagnosis and treatment of TB among patients attending a referral hospital in Northwest, Ethiopia. BMC Infectious Diseases doi: 10.1186/1471-2334-14-19
- Solomon Abebe Yimer, Elena Hailu, Yohannes Derese, Gunnar Aksel Bjune, Carol J. C. Holm-Hansen, (2013). Spoligotyping of Mycobacterium tuberculosis isolates among pulmonary tuberculosis patients in Amhara Region, Ethiopia. APMIS - Journal of Pathologiy, Microbiology and Immunology s. 878-885. doi: 10.1111/apm.12046
- Solomon Abebe Yimer, Mulualem Agonafir, Yohannes Derese, Yusuf Sani, Gunnar Aksel Bjune, Carol J. C. Holm-Hansen, (2012). Primary drug resistance to anti-tuberculosis drugs in major towns of Amhara region, Ethiopia. APMIS - Journal of Pathologiy, Microbiology and Immunology s. 503-509. doi: 10.1111/j.1600-0463.2011.02861.x
- Solomon Abebe Yimer, Carol J. C. Holm-Hansen, Gunnar Aksel Bjune, (2012). Assessment of knowledge and practice of private practitioners regarding tuberculosis control in Ethiopia. Journal of Infection in Developing Countries s. 13-19. doi: 10.3855/jidc.1927
- Solomon Abebe Yimer, Carol J C Holm-Hansen, Gunnar Aksel Bjune, (2011). The perspective of private practitioners regarding tuberculosis case detection and treatment delay in Amhara Region, Ethiopia: a cross-sectional study. BMC Research Notes doi: 10.1186/1756-0500-4-285
- Solomon Abebe Yimer, Alemayehu Godana, Shewit Kalayou, Tahira Riaz, Ephrem Debebe Zegeye, Getachew Tesfaye Beyene, Carol J C Holm-Hansen, Gunnstein Norheim, Markos Abebe, Abraham Aseffa, Tone Tonjum, (2010). Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence. Frontiers in Microbiology
- Carol J C Holm-Hansen, M Kirsti Vainio, (2009). Sequencing of viral genes. s. 203-215.
- Mecky Matee, Sayoki Mfinanga, Carol Holm-Hansen, (2009). Anti-TB drug resistance levels and patterns among Mycobacterium tuberculosis isolated from newly diagnosed cases of pulmonary tuberculosis in Dar es Salaam, Tanzania. APMIS - Journal of Pathologiy, Microbiology and Immunology s. 263-267. doi: 10.1111/j.1600-0463.2008.02429.x
- S Yimer, Carol Holm-Hansen, T Yimaldu, G Bjune, (2009). Evaluating an active case-finding strategy to identify smear-positive tuberculosis in rural Ethiopia. The International Journal of Tuberculosis and Lung Disease s. 1399-1404.
- Solomon Yimer, Carol Holm-Hansen, Tilahun Yimaldu, Gunnar Bjune, (2009). Health care seeking among pulmonary tuberculosis suspects and patients in rural Ethiopia: a community-based study. BMC Public Health doi: 10.1186/1471-2458-9-454
- Balthazar M Nyombi, Knut I Kristiansen, Gunnar Bjune, Fredrik Muller, Carol Holm-Hansen, (2008). Diversity of human immunodeficiency virus type 1 subtypes in Kagera and Kilimanjaro regions, Tanzania. AIDS Research and Human Retroviruses s. 761-769. doi: 10.1089/aid.2007.0311
- Balthazar M Nyombi, Watoky Nkya, Longin Barongo, Gunnar Bjune, Knut I Kristiansen, Fredrik Muller, Carol Holm-Hansen, (2008). Evolution of human immunodeficiency virus type 1 serotypes in northern Tanzania: a retrospective study. APMIS - Journal of Pathologiy, Microbiology and Immunology s. 507-514. doi: 10.1089/088922200415054
- Balthazar Nyombi, Carol Holm-Hansen, Knut I Kristiansen, Gunnar Bjune, Fredrik Müller, (2008). Prevalence of reverse transcriptase and protease mutations associated with antiretroviral drug resistance among drug-naïve HIV-1 infected pregnant women in Kagera and Kilimanjaro regions, Tanzania. AIDS research and therapy doi: 10.1186/1742-6405-5-13
- Balthazar Melchior Nyombi, Carol Holm-Hansen, Knut Ivan Kristiansen, Gunnar Aksel Bjune, Fredrik Muller, (2008). Prevalence of reverse transcriptase and protease mutations associated with antiretroviral drug resistance among drug-naive HIV-1 infected pregnant women in Kagera and Kilimanjaro regions, Tanzania. AIDS research and therapy
- Jagrati V Jani, Carol Holm-Hansen, Tufária Mussá, Arlinda Zango, Ivan Manhica, Gunnar Bjune, Ilesh V Jani, (2008). Assessment of measles immunity among infants in Maputo City, Mozambique. BMC Public Health doi: 10.1186/1471-2458-8-386
- Jagrati Jani-Bølstad, Carol Holm-Hansen, Tufária Mussá, Arlinda Zango, Ivan Manchica, Gunnar Aksel Bjune, Ilesh V. Jani, (2008). Assessment of measles immunity among infants in Maputo City, Mozambique. BMC Public Health
- F Abebe, Carol Holm-Hansen, HG Wiker, G Bjune, (2007). Progress in serodiagnosis of Mycobacterium tuberculosis infection. Scandinavian Journal of Immunology s. 176-191. doi: 10.1111/j.1365-3083.2007.01978.x
- Carol Holm-Hansen, Balthazar Nyombi, Mramba Nyindo, (2007). Saliva-based HIV testing among secondary school students in Tanzania using the OraQuick (R) rapid HIV1/2 antibody assay. Annals of the New York Academy of Sciences s. 461-466. doi: 10.1196/annals.1384.036
- GH Leyna, KS Mnyika, EJ Mmbaga, A Hussain, Elise Klouman, Carol Holm-Hansen, KI Klepp, (2007). Food insuffiency in rural Kilimanjaro,Tanzania. East African Medical Journal s. 163-171.
- Elia J Mmbaga, Akhtar Hussain, Germana H Leyna, Carol Holm-Hansen, Kagoma S Mnyika, Noel E Sam, Elise Klouman, Knut Inge Klepp, (2007). Trends in HIV-1 prevalence and risk behaviours over 15 years in a rural population in Kilimanjaro region of Tanzania. AIDS research and therapy doi: 10.1186/1742-6405-4-23
- Carol Holm-Hansen, (2006). Vaksiner mot hiv. Tidsskrift for Den norske legeforening (Tidsskriftet) s. 3117-3120.
- Clement B. Ndongmo, Danuta Pieniazek, Mona Holberg-Pettersen, Carol Holm-Hansen, Leopold Zekeng, Stig L. Jeansson, Lazare Kaptue, Marcia L. Kalish, (2006). HIV genetic diversity in Cameroon: Possible public health importance. AIDS Research and Human Retroviruses s. 812-816.
- Negussie Taffa, Johanne Sundby, Gunnar Aksel Bjune, Carol Holm-Hansen, (2002). HIV prevalence and sociocultural context of sexuality among youth in Addis Abeba, Ethiopia. Ethiopian Journal of Health Development
- Carol Holm-Hansen, Beate Stern, Siren Rustad, John Shao, Eva Birgitta Åsjø, (2000). V3 sequence analysis and biological characterization of HIV-1 isolates from asymptomatic and early symptomatic Tanzanian individuals. APMIS - Journal of Pathologiy, Microbiology and Immunology s. 608-616.
- Carol Holm-Hansen, Elly Baan, Eva Birgitta Åsjø, Flavia Rodica Pascu, Jaap Goudsmit, Jacques J. de Jong, (2000). Determinants for the syncytium-inducing phenotype of HIV-1 subtype F isolates are located in the V3 region. AIDS Research and Human Retroviruses s. 867-870.
- Solomon Abebe Yimer, Alemayehu Godana Birhanu, Kalayou Shewit, Tahira Riaz, Ephrem Debebe Zegeye, Getachew Tesfaye Beyene, Carol J C Holm-Hansen, Gunnstein Norheim, Markos Abebe, Abraham Aseffa, Tone Tonjum, (2016). First proteomic analysis of Mycobacterium tuberculosis lineage 7 differentially expressed proteins involved for growth.
- Solomon Abebe Yimer, Amine Namouchi, Tahira Riaz, Ephrem Debebe Zegeye, Alemayehu Godana, Carol J C Holm-Hansen, Gunnstein Norheim, Abraham Aseffa, Tone Tonjum, (2015). Genomic and proteomic analysis of Mycobacterium tuberculosis lineage 7 strains from Ethiopia. Oral presentation at the 46th Union World Conference on Lung Health Cape Town, South Africa: 2 December - 6 December 2015.
- Solomon Abebe Yimer, Amine Namouchi, Efrem Zegeye, Gunnstein Norheim, Carol J C Holm-Hansen, Abraham Aseffa, Tone Tonjum, (2015). The emerging Mycobacterium tuberculosis lineage 7 strains from Ethiopia. Oral presentation at the Top Gear in Science Research Workshop held from 19th - 20th June 2015, The Norwegian Academy of Science and Letters (DNVA), Oslo, Norway.
- Solomon Abebe Yimer, Gunnstein Norheim, Amine Namouchi, Efrem Zegeye, Wibeke Kinander, Shiferaw Bekele, Turid Mannsåker, Gunnar Aksel Bjune, Abraham Aseffa, Carol J C Holm-Hansen, (2015). Mycobacterium tuberculosis lineage 7 strains are associated with prolonged patient delay in pulmonary tuberculosis patients in Amhara Region, Ethiopia. Oral presentation at the World TB Summit to be held in London, UK 24th-26th March/2015.
- Solomon Abebe Yimer, Gunnstein Norheim, Amine Namouchi, Ephrem Debebe Zegeye, Wibeke Kinander, Tone Tonjum, Turid Mannsåker, Gunnar Aksel Bjune, Carol J C Holm-Hansen, (2015). Lineage 7 Mycobacterium tuberculosis strains are associated with longer patient delay in pulmonary TB patients.
- Solomon Yimer, Carol J C Holm-Hansen, Dag Gustav Gundersen Storla, Gunnar Aksel Bjune, (2014). Tuberculosis management time: an alternative parameter for measuring the tuberculosis infectious pool.
- Solomon Yimer, Wolfgang Egge-Jacobsen, Ephrem Debebe Zegeye, Gunnstein Norheim, Carol J C Holm-Hansen, Abraham Aseffa, Tone Tonjum, (2014). Unraveling unique posttranslational modification profiles in Mycobacterium tuberculosis lineage 7 strains from Ethiopia.
- Carol J. C. Holm-Hansen, (2012). Development of a rapid serological screening test for tuberculosis. Tropical medicine & international health s. 25-25.
- Solomon Abebe Yimer, C Holm-Hansen, G Bjune, (2009). Measuring the prevalence of sputum smear-positive tuberculosis in a rural district of Ethiopia: an active case finding.
- Carol Holm-Hansen, Inger Lise Haugen, Bjørn Haneberg, (2002). Bruk av spytt til påvisning av HIV-infeksjon. Genialt s. 16-18.
- B.M. Nyombi, Stig Leo Jeansson, Watoky Nkya, L. Barongo, Gunnar Aksel Bjune, Carol Holm-Hansen, (2002). Evolution of HIV-1 subtypes in Northern Tanzania: A retrospective study.
- Carol Holm-Hansen, Inger Lise Haugen, Mette Sannes, H. Willemsen, J. Pedersen, Gunnar Flåten, Jan Tomas Kjendli, Bjørn Haneberg, (2000). Antibodies to HIV can be detected in air-dried saliva.