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Antioxidants and the development of leukemia in children

Project

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Published

The project aims to investigate whether maternal antioxidant status, with a specific focus on selenium, during pregnancy is associated with the risk of later development of childhood leukemia.

Summary

In a context where radon is considered a possible risk factor for childhood leukemia, antioxidants have been suggested as a potential preventive measure. This project aims to investigate whether maternal antioxidant status, with a particular focus on selenium during pregnancy, is associated with the risk of later development of childhood leukemia. We will also assess the interaction between selenium status and other antioxidants, including essential and non-essential elements. The project will use questionnaire and biological data from MoBa, MoBa's copy of MFR, and the Cancer Registry in a nested case-control design. The project is part of the EU-funded project RadoNORM. Aggregate results from this study on antioxidants can be compared with results from similar studies conducted by national (ref. REK no. 469895) and international partners with the overarching goal of studying the association between radon and the risk of childhood leukemia development.

Project leader

Ida Henriette Caspersen, Folkehelseinstituttet

Project participants

Per Magnus, Folkehelseinstituttet
Siri Håberg, Folkehelseinstituttet
Dag Marcus Eide, Folkehelseinstituttet

Start

01.10.2022

End

31.12.2025

Financing

Research Council of Norway

Approvals

Regional Committees for Medical and Health Research Ethics (REK) - 536886

Project owner/ Project manager

Norwegian Institute of Public Health

Project manager

Ida Henriette Caspersen

Published