Even Fossum
Senior Researcher
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Department
Projects and publications
- Ignacio Garcia Llorente, Jon Bråte, Even Fossum, Andreas Rohringer, Line Victoria Moen, Olav Hungnes, Olav Fjære, Kyriako Zaragkoulias, Karoline Bragstad, (2024). Recombinant SARS-CoV-2 Delta/Omicron BA.5 emerging in an immunocompromised long-term infected COVID-19 patient. Scientific Reports doi: 10.1038/s41598-024-75241-3
- Gro Tunheim, Even Fossum, Anna Hayman Robertson, Gunnar Øyvind Isaksson Rø, Adity Chopra, John T. Vaage, Elisabeth Lea Vikse, Anne-Marte Bakken Kran, Per Minor Magnus, Lill Trogstad, Siri Mjaaland, Olav Hungnes, Fridtjof Lund-Johansen, (2024). Characterization of the SARS-CoV-2 antibody landscape in Norway in the late summer of 2022: high seroprevalence in all age groups with patterns of primary Omicron infection in children and hybrid immunity in adults. BMC Infectious Diseases s. 1-20. doi: 10.1186/s12879-024-09670-w
- Even Fossum, Andreas Rohringer, Torstein Aune, Kjersti Margrethe Rydland, Karoline Bragstad, Olav Hungnes, (2024). Antigenic drift and immunity gap explain reduction in protective responses against influenza A(H1N1)pdm09 and A(H3N2) viruses during the COVID-19 pandemic: a cross-sectional study of human sera collected in 2019, 2021, 2022, and 2023. Virology Journal doi: 10.1186/s12985-024-02326-w
- Sopisa Benjakul, Aina Karen Anthi, Heidi Anette Kolderup, Marina Vaysburd, Heidrun Elisabeth Lode, D Mallery, Even Fossum, Elisabeth Lea Vikse, Anna Albecka, Aleksandr Ianevski, Denis Kaynov, Karine Flem Karlsen, Siri Aastedatter Sakya, Mari Nyquist-Andersen, torleif gjølberg, Morten Carsten Moe, Magnar Bjørås, Inger Sandlie, Leo C. James, Jan Terje Andersen, (2023). A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery. PNAS Nexus s. 1-15. doi: 10.1093/pnasnexus/pgad403
- Marita Westhrin, Jana Blazevski, Ana Textor, Pegah Abdollahi, Ramakrishna Prabhu Gopalakrishnan, Linda Thuy Ngo, Peter Olaf Hofgaard, Julia Heinzelbecker, Sonja Bobic, Even Fossum, Heidi Cecilie Larsen Spång, Ranveig Braathen, Bjarne Bogen, (2023). Id-neoantigen vaccine induces therapeutic CD8<sup>+</sup> T cells against multiple myeloma: H chain-loss escapees cause FLC MM. Journal for ImmunoTherapy of Cancer (JITC) s. 1-13. doi: 10.1136/jitc-2023-006944
- Ina Charlotta Werninghaus, Daniëla Maria Hinke, Even Fossum, Bjarne Bogen, Ranveig Braathen, (2023). Neuraminidase delivered as an APC-targeted DNA vaccine induces protective antibodies against influenza. Molecular Therapy s. 2188-2205. doi: 10.1016/j.ymthe.2023.03.012
- Elisabeth Lea Vikse, Even Fossum, Magnhild Sekse Erdal, Olav Hungnes, Karoline Bragstad, (2023). Poor neutralizing antibody responses against SARS-CoV-2 Omicron BQ.1.1 and XBB in Norway in October 2022. Influenza and Other Respiratory Viruses s. 1-6. doi: 10.1111/irv.13144
- Eva Domenjo-Vila, Valentina Casella, Ryutaro Iwabuchi, Even Fossum, Mireia Pedragosa, Quim Castellví, Paula Cebollada Rica, Tsuneyasu Kaisho, Kazutaka Terahara, Gennady Bocharov, Jordi Argilaguet, Andreas Meyerhans, (2023). XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections. Cell reports doi: 10.1016/j.celrep.2023.112123
- Daniëla Maria Hinke, Tor Kristian Andersen, Ramakrishna Prabhu Gopalakrishnan, Lise Madelen Skullerud, Ina Charlotta Werninghaus, Gunnveig Grødeland, Even Fossum, Ranveig Braathen, Bjarne Bogen, (2022). Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses. Cell reports s. 1-27. doi: 10.1016/j.celrep.2022.110901
- Demo Yemane Tesfaye, Sonja Bobic, Anna Karin Christina Lysén, Peter Csaba Huszthy, Arnar Gudjonsson, Ranveig Braathen, Bjarne Bogen, Even Fossum, (2022). Targeting Xcr1 on dendritic cells rapidly induce Th1-associated immune responses that contribute to protection against influenza infection. Frontiers in Immunology s. 1-13. doi: 10.3389/fimmu.2022.752714
- Le He, Marie-Pierre Valignat, Lichen Zhang, Lena Gelard, Fanghui Zhang, Valentin Le Guen, Stéphane Audebert, Luc Camoin, Even Fossum, Bjarne Bogen, Hui Wang, Sandrine Henri, Romain Roncagalli, Olivier Theodoly, Yinming Liang, Marie Malissen, Bernard Malissen, (2021). ARHGAP45 controls naïve T- and B- cell entry into lymph nodes and T-cell progenitor thymus seeding. EMBO Reports s. 1-19. doi: 10.15252/embr.202052196
- Anna Karin Christina Lysén, Arnar Gudjonsson, Demo Yemane Tesfaye, Sonja Bobic, Malin C. Bern, Bjarne Bogen, Even Fossum, (2021). Intranasal delivery of a cDC1 targeted influenza vaccine with poly(I:C) enhances T cell responses and protects against influenza infection. Scandinavian Journal of Immunology s. 1-12. doi: 10.1111/sji.13128
- Even Fossum, Demo Yemane Tesfaye, Sonja Bobic, Arnar Gudjonsson, Ranveig Braathen, Mireille H. Lahoud, Irina Caminschi, Bjarne Bogen, (2020). Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response . Journal of Immunology s. 661-673. doi: 10.4049/jimmunol.1901119
- Ranveig Braathen, Heidi Cecilie Larsen Spång, Daniëla Maria Hinke, Jana Blazevski, Sonja Bobic, Even Fossum, Bjarne Bogen, (2020). A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza . Molecular therapy. Methods & clinical development s. P378-P392. doi: 10.1016/j.omtm.2020.01.007
- Gunnveig Grødeland, Even Fossum, Bjarne Bogen, (2019). Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs. Vaccine s. 1280-1285. doi: 10.1016/j.vaccine.2019.11.084
- Demo Yemane Tesfaye, Arnar Gudjonsson, Bjarne Bogen, Even Fossum, (2019). Targeting conventional dendritic cells to fine-tune antibody responses. Frontiers in Immunology s. 1-8. doi: 10.3389/fimmu.2019.01529
- Arnar Gudjonsson, Tor Kristian Andersen, Vibeke Sundvold Gjerstad, Bjarne Bogen, Even Fossum, (2019). Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice. Frontiers in Immunology s. 1-12. doi: 10.3389/fimmu.2019.01086
- Anna Karin Christina Lysén, Ranveig Braathen, Arnar Gudjonsson, Demo Yemane Tesfaye, Bjarne Bogen, Even Fossum, (2019). Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site. Scientific Reports s. 1-11. doi: 10.1038/s41598-018-38080-7
- Ranveig Braathen, Heidi Cecilie Larsen Spång, Mona Mari Lindeberg, Even Fossum, Gunnveig Grødeland, Agnete Fredriksen, Bjarne Bogen, (2018). The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccine Are Influenced by Specificity for APC Surface Molecules. ImmunoHorizons s. 38-53. doi: 10.4049/immunohorizons.1700038
- Charlotte Deloizy, Even Fossum, Christophe Barnier-Quer, Céline Urien, Tiphany Chrun, Audrey Duval, Maelle Codjovi, Edwige Bouguyon, Pauline Maisonnasse, Pierre-Louis Hervé, Céline Barc, Olivier Boulesteix, Jérémy Pezant, Christophe Chevalier, Nicolas Collin, Marc Dalod, Bjarne Bogen, Nicolas Bertho, Isabelle Schwartz-Cornil, (2017). The anti-influenza M2e antibody response is promoted by XCR1 targeting in pig skin. Scientific Reports s. 1-12. doi: 10.1038/s41598-017-07372-9
- Arnar Gudjonsson, Anna Karin Christina Lysén, Sreekumar Balan, Vibeke Sundvold Gjerstad, Catharina Arnold-Schrauf, Lisa Maria Richter, Espen Sønderaal Bækkevold, Marc Dalod, Bjarne Bogen, Even Fossum, (2017). Targeting influenza virus hemagglutinin to Xcr1+ dendritic cells in the absence of receptor-mediated endocytosis enhances protective antibody responses. Journal of Immunology s. 2785-2795. doi: 10.4049/jimmunol.1601881
- Peng Zhou, Yok Teng Chionh, Sergio Erdal Irac, Matae Ahn, Justin Han Jia Ng, Even Fossum, Bjarne Bogen, Florent Ginhoux, Aaron T Irving, Charles-Antoine Dutertre, Lin-Fa Wang, (2016). Unlocking bat immunology: Establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages. Scientific Reports doi: 10.1038/srep38597
- Laurence Ardouin, Hervé Luche, Rabie Chelbi, Sabrina Carpentier, Alaa Shawket, Frédéric Montanana Sanchis, Camille Santa Maria, Pierre Grenot, Yannick Alexandre, Claude Gregoire, Anissa Fries, Thien-Phong Vu Manh, Samira Tamoutounour, Karine Crozat, Elena Tomasello, Audrey Jorquera, Even Fossum, Bjarne Bogen, Hiroaki Azukizawa, Marc Bajenoff, Sandrine Henri, Marc Dalod, Bernard Malissen, (2016). Broad and largely concordant molecular changes characterize tolerogenic and immunogenic dendritic cell maturation in thymus and periphery. Immunity s. 305-318. doi: 10.1016/j.immuni.2016.07.019
- Martin Guilliams, Charles-Antoine Dutertre, Charlotte L. Scott, Naomi McGovern, Dorine Sichien, Svetoslav Chakarov, Sofie Van Gassen, Jinmiao Chen, Michael Poidinger, Sofie De Prijck, Simon J. Tavernier, Ivy Low, Sergio Erdal Irac, Citra Nurfarah Mattar, Hermi Rizal Sumatoh, Gillian Hui Ling Low, Tam John Kit Chung, Dedrick Kok Hong Chan, Ker Kan Tan, Tony Lim Kiat Hon, Even Fossum, Bjarne Bogen, Mahesh Choolani, Jerry Kok Yen Chan, Anis Larbi, Hervé Luche, Sandrine Henri, Yvan Saeys, Evan William Newell, Bart N. Lambrecht, Bernard Malissen, Florent Ginhoux, (2016). Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species. Immunity s. 669-684. doi: 10.1016/j.immuni.2016.08.015
- Charlotte Deloizy, Edwige Bouguyon, Even Fossum, Peter Sebo, Radim Osička, Angelique Bole, Michel Pierres, Stephane Biacchesi, Marc Dalod, Bjarne Bogen, Nicolas Bertho, Isabelle Schwartz-Cornil, (2016). Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1. Developmental and Comparative Immunology s. 31-40. doi: 10.1016/j.dci.2016.06.015
- György Nagy, Peter Csaba Huszthy, Even Fossum, Yrjö Konttinen, Britt Nakken, Peter Szodoray, (2015). Selected aspects in the pathogenesis of autoimmune diseases. Mediators of Inflammation doi: 10.1155/2015/351732
- Gunnveig Grødeland, Even Fossum, Bjarne Bogen, (2015). Polarizing T and B cell responses by APC-targeted subunit vaccines. Frontiers in Immunology doi: 10.3389/fimmu.2015.00367
- Dorothea Terhorst, Even Fossum, Anna Baranska, Samira Tamoutounour, Camille Malosse, Mattia Garbani, Reinhard Braun, Elmira Lechat, Reto Crameri, Bjarne Bogen, Sandrine Henri, Bernard Malissen, (2015). Laser-Assisted Intradermal Delivery of Adjuvant-Free Vaccines Targeting XCR1+ Dendritic Cells Induces Potent Antitumoral Responses. Journal of Immunology s. 5895-5902. doi: 10.4049/jimmunol.1500564
- Even Fossum, Gunnveig Grødeland, Dorothea Terhorst, Anders Tveita, Elisabeth Lea Vikse, Siri Mjaaland, Sandrine Henri, Bernard Malissen, Bjarne Bogen, (2015). Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8+ T-cell responses against influenza virus. European Journal of Immunology s. 624-635. doi: 10.1002/eji.201445080
- Sreekumar Balan, Vincent Ollion, Nicholas Colletti, Rabie Chelbi, Frederic Montanana-Sanchis, Hong Liu, Thien-Phong Vu Manh, Cindy Sanchez, Juliette Savoret, Ivan Perrot, Anne-Claire Doffin, Even Fossum, Didier Bechlian, Christian Chabannon, Bjarne Bogen, Carine Asselin-Paturel, Michael Shaw, Timothy Soos, Christophe Caux, Jenny Valladeau-Guilemond, Marc Dalod, (2014). Human XCR1<sup>+</sup> dendritic cells derived in vitro from CD34 <sup>+</sup> progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells. Journal of Immunology s. 1622-1635. doi: 10.4049/jimmunol.1401243
- Charles-Antoine Dutertre, Jean-Pierre Jourdain, Magali Rancez, Sonia Amraoui, Even Fossum, Bjarne Bogen, Cindy Sanchez, Anne Couëdel-Courteille, Yolande Richard, Marc Dalod, Vincent Feuillet, Rémi Cheynier, Anne Hosmalin, (2014). TLR3-responsive, XCR1<sup>+</sup>, CD141(BDCA-3)<sup>+</sup>/ CD8α<sup>+</sup>- equivalent dendritic cells uncovered in healthy and simian immunodeficiency virus-infected rhesus macaques. Journal of Immunology s. 4697-4708. doi: 10.4049/jimmunol.1302448
- Karine Crozat, Samira Tamoutounour, Thien-Phong Manh, Even Fossum, Hervé Luche, Laurence Ardouin, Martin Guilliams, Hiroaki Azukizawa, Bjarne Bogen, Bernard Malissen, Sandrine Henri, Marc Dalod, (2011). Cutting Edge: Expression of XCR1 Defines Mouse Lymphoid-Tissue Resident and Migratory Dendritic Cells of the CD8 alpha(+) Type. Journal of Immunology s. 4411-4415. doi: 10.4049/jimmunol.1101717
- KNUT-HAAKON STENSÆTH, Even Fossum, PAVEL HOFFMANN, Arild Mangschau, Nils-Einar Klow, (2011). Clinical characteristics and role of early cardiac magnetic resonance imaging in patients with suspected ST-elevation myocardial infarction and normal coronary arteries. The International Journal of Cardiac Imaging s. 355-365. doi: 10.1007/s10554-010-9671-7
- Olav Hungnes, Trine Hessevik Paulsen, Andreas Rohringer, Elina Marjukka Seppälä, Håkon Bøås, Even Fossum, Jeanette Stålcrantz, Birgitte Klüwer, Kjersti Margrethe Rydland, Torstein Aune, Karoline Bragstad, (2024). Influenza Virological and Epidemiological 2023-24 season report, October 2024.
- Olav Hungnes, Trine Hessevik Paulsen, Andreas Rohringer, Elina Marjukka Seppälä, Håkon Bøås, Even Fossum, Jeanette Stålcrantz, Birgitte Klüwer, Kjersti Margrethe Rydland, Torstein Aune, Karoline Bragstad, (2024). Influenza Virological and Epidemiological season report prepared for the WHO Consultation on the Composition of Influenza Virus Vaccines for the Southern Hemisphere 2025.
- Olav Hungnes, Trine Hessevik Paulsen, Andreas Rohringer, Elina Marjukka Seppälä, Håkon Bøås, Jesper Dahl, Even Fossum, Jeanette Stålcrantz, Birgitte Klüwer, Kjersti Margrethe Rydland, Torstein Aune, Karoline Bragstad, (2024). Interim influenza Virological and Epidemiological season report prepared for the WHO Consultation on the Composition of Influenza Virus Vaccines for the Northern Hemisphere 2024/2025.
- Olav Hungnes, Trine Hessevik Paulsen, Andreas Rohringer, Elina Marjukka Seppälä, Håkon Bøås, Jesper Dahl, Even Fossum, Jeanette Stålcrantz, Birgitte Klüwer, Kjersti Margrethe Rydland, Torstein Aune, Karoline Bragstad, (2023). Influenza Virological and Epidemiological season report prepared for the WHO Consultation on the Composition of Influenza Virus Vaccines for the Southern Hemisphere 2024, October 2023.
- Olav Hungnes, Trine Hessevik Paulsen, Andreas Rohringer, Elina Marjukka Seppälä, Håkon Bøås, Jesper Dahl, Even Fossum, Jeanette Stålcrantz, Birgitte Klüwer, Kjersti Margrethe Rydland, Torstein Aune, Karoline Bragstad, (2023). Influenza Virological and Epidemiological season report, October 2023.
- Olav Hungnes, Trine Hessevik Paulsen, Andreas Rohringer, Elina Marjukka Seppälä, Ragnhild Tønnessen, Håkon Bøås, Jesper Dahl, Even Fossum, Jeanette Stålcrantz, Birgitte Klüwer, Kjersti Margrethe Rydland, Torstein Aune, Karoline Bragstad, (2023). Interim Influenza Virological and Epidemiological season report prepared for the WHO Consultation on the Composition of Influenza Virus Vaccines for the Northern Hemisphere 2023/2024.
- Even Fossum, Andreas Rohringer, Torstein Aune, Kjersti Margrethe Rydland, Karoline Bragstad, Olav Hungnes, (2024). Correction to: Antigenic drift and immunity gap explain reduction in protective responses against influenza A(H1N1)pdm09 and A(H3N2) viruses during the COVID-19 pandemic: a cross-sectional study of human sera collected in 2019, 2021, 2022, and 2023 (Virology Journal, (2024), 21, 1, (57), 10.1186/s12985-024-02326-w). Virology Journal doi: 10.1186/s12985-024-02341-x
- Gunnveig Grødeland, Even Fossum, Randi Eikeland, Yngve Stiansen, Ina Marie Sigurdsen, (2024). Stoppa sal etter skepsis – ny vaksine nærmar seg.
- Even Fossum, (2022). Hvorfor organtransplanterte personer bør takke ja til vaksinenering.. Norsk Farmaceutisk Tidsskrift (NFT) s. 36-37.
- Even Fossum, Tor Kristian Andersen, Ranveig Braathen, (2022). Når gener blir vaksine. Norsk Farmaceutisk Tidsskrift (NFT) s. 21-24.
- Even Fossum, Gunnveig Grødeland, Svenn-Erik Mamelund, (2022). Pandemier og samfunn.
- Daniëla Maria Hinke, Tor Kristian Andersen, Lise Madelen Skullerud, Ina Werninghaus, Gunnveig Grødeland, Even Fossum, Ranveig Braathen, Bjarne Bogen, (2021). Antigen bivalency in antigen presenting cell-targeted vaccines enhances humoral responses.
- Anna Karin Christina Lysén, Ranveig Braathen, Arnar Gudjonsson, Demo Yemane Tesfaye, Bjarne Bogen, Even Fossum, (2020). Author Correction: Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site (Scientific Reports, (2019), 9, 1, (1820), 10.1038/s41598-018-38080-7). Scientific Reports doi: 10.1038/s41598-020-62688-3
- Ane Marie Anderson, Arnar Gudjonsson, Even Fossum, Gunnveig Grødeland, (2020). Gjør Norge nok for å bekjempe covid-19?. Morgenbladet
- Daniëla Maria Hinke, Heidi Spång, Even Fossum, Gunnveig Grødeland, Bjarne Bogen, Ranveig Braathen, (2018). MHC class II targeted DNA vaccine is most efficient in the induction of protective antibodies against influenza.
- Britt Nakken, György Nagy, Peter Csaba Huszthy, Even Fossum, Yrjö Konttinen, Peter Szodoray, (2015). Inflammatory mediators in autoimmunity and systemic autoimmune diseases. Mediators of Inflammation doi: 10.1155/2015/878712
- Even Fossum, Nils Anders Leversen, Harald G Wiker, Bjarne Bogen, (2011). Targeted Vaccibodies against Mycobacterium tuberculosis. Scandinavian Journal of Immunology s. 383-384.
- Ranveig Braathen, Agnete Fredriksen, Heidi Cecilie Larsen Spång, Mona Mari Lindeberg, Even Fossum, Bjarne Bogen, (2011). Targeting DNA Vaccines against Influenza, can the Immune Response be Orchestered?. Scandinavian Journal of Immunology s. 382-383.